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1

Commentary on: `Effect of purified soluble urokinase receptor on the plasminogen prourokinase activation system' by N. Behrendt and K. Dano, FEBS Letters, 393 (1996) 31–36

Abd Al-Roof Higazi

Journal:

Year:

1997

Language:

english

File:

PDF, 201 KB

english, 1997

2

Regulation of neutrophil activation by oleic acid

Higazi, Abd Al-Roof, Barghouti, Iyad I.

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Year:

1994

Language:

english

File:

PDF, 433 KB

english, 1994

3

Opposing effects of HNP1 (Î±-defensin-1) on plasma cholesterol and atherogenesis

Higazi, Mohamed, Abdeen, Suhair, Abu-Fanne, Rami, Heyman, Samuel N., Masarwy, Aseel, Bdeir, Khalil, Maraga, Emad, Cines, Douglas B., Higazi, Abd Al-Roof, Bader, Michael

Journal:

Year:

2020

File:

PDF, 837 KB

2020

4

uPA modulates the age-dependent effect of brain injury on cerebral hemodynamics through LRP and ERK MAPK

Armstead, William M, Cines, Douglas B, Bdeir, Khalil H, Bdeir, Yasmina, Stein, Sherman C, Higazi, Abd Al-Roof

Journal:

Journal of Cerebral Blood Flow and Metabolism

Year:

2008

Language:

english

File:

PDF, 317 KB

english, 2008

5

The Structure of Lipoprotein(a) and Ligand-Induced Conformational Changes †

Weisel, John W., Nagaswami, Chandrasekaran, Woodhead, John L., Higazi, Abd Al-Roof, Cain, William J., Marcovina, Santica M., Koschinsky, Marlys L., Cines, Douglas B., Bdeir, Khalil

Journal:

Year:

2001

Language:

english

File:

PDF, 585 KB

english, 2001

6

tPA variant tPA-A 296-299 Prevents impairment of cerebral autoregulation and necrosis of hippocampal neurons after stroke by inhibiting upregulation of ET-1

Armstead, William M, Hekierski, Hugh, Yarovoi, Serge, Higazi, Abd Al-Roof, Cines, Douglas B.

Journal:

Journal of Neuroscience Research

Year:

2017

Language:

english

File:

PDF, 754 KB

english, 2017

7

Urokinase-derived peptides regulate vascular smooth muscle contraction in vitro and in vivo

HAJ-YEHIA, ABDULLAH, NASSAR, TAHER, SACHAIS, BRUCE S., KUO, ALICE, BDEIR, KHALIL, AL-MEHDI, ABU BAKR, MAZAR, ANDREW, CINES, DOUGLAS B., HIGAZI, ABD AL-ROOF

Journal:

The FASEB Journal

Year:

2000

Language:

english

File:

PDF, 356 KB

english, 2000

8

α-Defensin: Link between inflammation and atherosclerosis

Hisham Nassar, Ehud Lavi, Sa’ed Akkawi, Khalil Bdeir, Samuel N. Heyman, P.N. Raghunath, John Tomaszewski, Abd Al-Roof Higazi

Journal:

Atherosclerosis

Year:

2007

Language:

english

File:

PDF, 494 KB

english, 2007

9

Unesterified Long Chain Fatty Acids Inhibit the Binding of Single Chain Urokinase to the Urokinase Receptor †

Higazi, Abd Al-Roof, Aceto, Joseph F., Kniss, Douglas, Upson, Rosalyn, Cohen, Robert, Dichek, David A., Cines, Douglas B.

Journal:

Year:

1996

Language:

english

File:

PDF, 350 KB

english, 1996

10

Interactions of Platelet Factor 4 with the Vessel Wall

Sachais, Bruce S, Higazi, Abd Al-Roof, Cines, Douglas B, Poncz, Mortimer, Kowalska, M. Anna

Journal:

Seminars in Thrombosis and Hemostasis

Year:

2004

Language:

english

File:

PDF, 206 KB

english, 2004

11

Defensin Stimulates the Binding of Lipoprotein (a) to Human Vascular Endothelial and Smooth Muscle Cells

Higazi, Abd Al-Roof, Lavi, Ehud, Bdeir, Khalil, Ulrich, Anthony M., Jamieson, Dara G., Rader, Daniel J., Usher, David C., Kane, William, Ganz, Tomas, Cines, Douglas B.

Journal:

Year:

1997

Language:

english

File:

PDF, 335 KB

english, 1997

12

tPA contributes to impairment of ATP and Ca sensitive K channel mediated cerebrovasodilation after hypoxia/ischemia through upregulation of ERK MAPK

William M. Armstead, John Riley, Douglas B. Cines, Abd Al-Roof Higazi

Journal:

Year:

2011

Language:

english

File:

PDF, 476 KB

english, 2011

13

Urokinase Plasminogen Activator Impairs SNP and PGE 2 Cerebrovasodilation after Brain Injury through Activation of LRP and ERK MAPK

Armstead, William M., Christine, Amy J., Higazi, Abd Al-Roof, Cines, Douglas B.

Journal:

Journal of Neurotrauma

Year:

2008

Language:

english

File:

PDF, 182 KB

english, 2008

14

RBC-coupled tPA Prevents Whereas tPA Aggravates JNK MAPK-Mediated Impairment of ATP- and Ca-Sensitive K Channel-Mediated Cerebrovasodilation After Cerebral Photothrombosis

William M. Armstead, Kumkum Ganguly, John Riley, Sergei Zaitsev, Douglas B. Cines, Abd Al-Roof Higazi, Vladimir R. Muzykantov

Journal:

Translational Stroke Research

Year:

2012

Language:

english

File:

PDF, 214 KB

english, 2012

15

Urokinase Plasminogen Activator Regulates Pulmonary Arterial Contractility and Vascular Permeability in Mice

Nassar, Taher, Yarovoi, Serge, Fanne, Rami Abu, Waked, Otailah, Allen, Timothy C., Idell, Steven, Cines, Douglas B., Higazi, Abd Al-Roof

Journal:

American Journal of Respiratory Cell and Molecular Biology

Year:

2011

Language:

english

File:

PDF, 756 KB

english, 2011

16

Role of tissue plasminogen activator in clinical aggravation of experimental autoimmune encephalomyelitis and its therapeutic potential

Mizrachi, Tehila, Gur-Wahnon, Devorah, Al-Roof Higazi, Abd, Brenner, Talma

Journal:

Cellular Immunology

Year:

2020

Language:

english

File:

PDF, 1.26 MB

english, 2020

17

α-Defensins Induce a Post-translational Modification of Low Density Lipoprotein (LDL) That Promotes Atherosclerosis at Normal Levels of Plasma Cholesterol

Abu-Fanne, Rami, Maraga, Emad, Abd-Elrahman, Ihab, Hankin, Aviel, Blum, Galia, Abdeen, Suhair, Hijazi, Nuha, Cines, Douglas B., Higazi, Abd Al-Roof

Journal:

Journal of Biological Chemistry

Year:

2016

Language:

english

File:

PDF, 2.48 MB

english, 2016

18

Lysis of Plasma Clots by Urokinase-Soluble Urokinase Receptor Complexes

Higazi, Abd Al-Roof, Bdeir, Khalil, Hiss, Edna, Arad, Shira, Kuo, Alice, Barghouti, Iyad, Cines, Douglas B.

Journal:

Year:

1998

File:

PDF, 1.27 MB

1998

19

uPA impairs cerebrovasodilation after hypoxia/ischemia through LRP and ERK MAPK

William M. Armstead, Douglas B. Cines, Khalil Bdeir, Irina Kulikovskaya, Sherman C. Stein, Abd Al-Roof Higazi

Journal:

Year:

2008

Language:

english

File:

PDF, 1.44 MB

english, 2008

20

tPA-S481A Prevents Neurotoxicity of Endogenous tPA in Traumatic Brain Injury

Armstead, William M., Riley, John, Yarovoi, Serge, Cines, Douglas B., Smith, Douglas H., Higazi, Abd Al-Roof

Journal:

Journal of Neurotrauma

Year:

2012

Language:

english

File:

PDF, 464 KB

english, 2012

21

Neutrophil α-Defensins Cause Lung Injury by Disrupting the Capillary–Epithelial Barrier

Bdeir, Khalil, Higazi, Abd Al-Roof, Kulikovskaya, Irina, Christofidou-Solomidou, Melpo, Vinogradov, Sergei A., Allen, Timothy C., Idell, Steven, Linzmeier, Rose, Ganz, Tomas, Cines, Douglas B.

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2010

Language:

english

File:

PDF, 1.85 MB

english, 2010

22

PAI-1-Derived Peptide EEIIMD Prevents Hypoxia/Ischemia-Induced Aggravation of Endothelin- and Thromboxane-Induced Cerebrovasoconstriction

Armstead, William M., Riley, John, Cines, Douglas B., Higazi, Abd Al-Roof

Journal:

Neurocritical Care

Year:

2014

Language:

english

File:

PDF, 302 KB

english, 2014

23

Regulation of Airway Contractility by Plasminogen Activators through N-Methyl-D-Aspartate Receptor–1

Nassar, Taher, Yarovoi, Serge, Fanne, Rami Abu, Akkawi, Sa'ed, Jammal, Mahmud, Allen, Timothy Craig, Idell, Steven, Cines, Douglas B., Higazi, Abd Al-Roof

Journal:

American Journal of Respiratory Cell and Molecular Biology

Year:

2010

Language:

english

File:

PDF, 1.07 MB

english, 2010

24

Release of IL-6 After Stroke Contributes to Impaired Cerebral Autoregulation and Hippocampal Neuronal Necrosis Through NMDA Receptor Activation and Upregulation of ET-1 and JNK

Armstead, William M., Hekierski, Hugh, Pastor, Philip, Yarovoi, Serge, Higazi, Abd Al-Roof, Cines, Douglas B.

Journal:

Translational Stroke Research

Year:

2018

Language:

english

File:

PDF, 1.12 MB

english, 2018

25

Neutralizing the neurotoxic effects of exogenous and endogenous tPA

Armstead, William M, Nassar, Taher, Akkawi, Saed, Smith, Douglas H, Chen, Xiao-Han, Cines, Douglas B, Higazi, Abd Al-Roof

Journal:

Nature Neuroscience

Year:

2006

Language:

english

File:

PDF, 387 KB

english, 2006

26

B-cell markers from the BAFF family as predictors for experimental autoimmune myasthenia gravis aggravation in mice lacking plasminogen activator components

Brenner, Talma, Mizrachi, Tehila, Gur-Wahnon, Devorah, Sicsic, Camille, Higazi, Abd Al-Roof

Journal:

Journal of Neuroimmunology

Year:

2014

Language:

english

File:

PDF, 53 KB

english, 2014

27

Blood–brain barrier permeability and tPA-mediated neurotoxicity

Rami Abu Fanne, Taher Nassar, Sergei Yarovoi, Anwar Rayan, Itschak Lamensdorf, Michael Karakoveski, Polianski Vadim, Mahmud Jammal, Douglas B. Cines, Abd Al-Roof Higazi

Journal:

Neuropharmacology

Year:

2010

Language:

english

File:

PDF, 1.28 MB

english, 2010

28

tPA contributes to impaired NMDA cerebrovasodilation after traumatic brain injury through activation of JNK MAPK

Armstead, William M, Willis Kiessling, J, Riley, John, Cines, Douglas B, Higazi, Abd Al-Roof

Journal:

Neurological Research

Year:

2011

Language:

english

File:

PDF, 170 KB

english, 2011

29

REGULATION OF SINGLE CHAIN UROKINASE BY SMALL PEPTIDES

Abd Al-Roof Higazi, Douglas Cines

Journal:

Thrombosis Research

Year:

1996

Language:

english

File:

PDF, 739 KB

english, 1996

30

Combination therapy with glucagon and a novel plasminogen activator inhibitor-1-derived peptide enhances protection against impaired cerebrovasodilation during hypotension after traumatic brain injury through inhibition of ERK and JNK MAPK

Armstead, William M, Riley, John, Cines, Douglas B, Higazi, Abd Al-Roof

Journal:

Neurological Research

Year:

2012

Language:

english

File:

PDF, 646 KB

english, 2012

31

Soluble urokinase receptor conjugated to carrier red blood cells binds latent pro-urokinase and alters its functional profile

Juan-Carlos Murciano, Abd Al-Roof Higazi, Douglas B. Cines, Vladimir R. Muzykantov

Journal:

Journal of Controlled Release

Year:

2009

Language:

english

File:

PDF, 367 KB

english, 2009

32

Tissue plasminogen activator involvement in experimental autoimmune myasthenia gravis: Aggravation and therapeutic potential

Gur-Wahnon, Devorah, Mizrachi, Tehila, Wald-Altman, Shane, Higazi, Abd Al-Roof, Brenner, Talma

Journal:

Journal of Autoimmunity

Year:

2014

Language:

english

File:

PDF, 828 KB

english, 2014

33

Glucagon Protects Against Impaired NMDA-Mediated Cerebrovasodilation and Cerebral Autoregulation during Hypotension after Brain Injury by Activating cAMP Protein Kinase A and Inhibiting Upregulation of tPA

Armstead, William M., Kiessling, J. Willis, Cines, Douglas B., Higazi, Abd Al-Roof

Journal:

Journal of Neurotrauma

Year:

2011

Language:

english

File:

PDF, 422 KB

english, 2011

34

Inhibition of neutrophil activation by fibrinogen

Abd Al-Roof Higazi, Iyad I. Barghouti, Suhail K. Ayesh, Michael Mayer, Yaacov Matzner

Journal:

Year:

1994

Language:

english

File:

PDF, 513 KB

english, 1994

35

Altered NO Function Contributes to Impairment of uPA and tPA Cerebrovasodilation after Brain Injury

Armstead, William M., Cines, Douglas B., Al-Roof Higazi, Abd

Journal:

Journal of Neurotrauma

Year:

2004

Language:

english

File:

PDF, 294 KB

english, 2004

36

Enhanced Activity of Plasmin and Plasminogen Activation in the Presence of Oleic Acid

ABD AL-ROOF HIGAZI, MICHAEL MAYER

Journal:

Annals of the New York Academy of Sciences

Year:

1992

Language:

english

File:

PDF, 101 KB

english, 1992

37

tPA-S 481 A Prevents Impairment of Cerebrovascular Autoregulation by Endogenous tPA after Traumatic Brain Injury by Upregulating p38 MAPK and Inhibiting ET-1

Armstead, William M., Bohman, Leif-Erik, Riley, John, Yarovoi, Serge, Higazi, Abd Al-Roof, Cines, Douglas B.

Journal:

Journal of Neurotrauma

Year:

2013

Language:

english

File:

PDF, 474 KB

english, 2013

38

Tissue-Type Plasminogen Activator-A 296–299 Prevents Impairment of Cerebral Autoregulation After Stroke Through Lipoprotein-Related Receptor–Dependent Increase in cAMP and p38

Armstead, William M., Riley, John, Yarovoi, Serge, Higazi, Abd Al-Roof, Cines, Douglas B.

Journal:

Year:

2016

Language:

english

File:

PDF, 1.08 MB

english, 2016

39

A peptide derived from the nonreceptor binding region of urokinase plasminogen activator (uPA) inhibits tumor progression and angiogenesis and induces tumor cell death in vivo

GUO, YONGJING, HIGAZI, ABD AL-ROOF, ARAKELIAN, ANI, SACHAIS, BRUCE S., CINES, DOUGLAS, GOLDFARB, RONALD H., JONES, TERENCE R., KWAAN, H., MAZAR, ANDREW P., RABBANI, SHAFAAT A.

Journal:

The FASEB Journal

Year:

2000

Language:

english

File:

PDF, 537 KB

english, 2000

40

Plasminogen activators contribute to age-dependent impairment of NMDA cerebrovasodilation after brain injury

William M. Armstead, Douglas B. Cines, Abd Al-Roof Higazi

Journal:

Developmental Brain Research

Year:

2005

Language:

english

File:

PDF, 395 KB

english, 2005

41

The effect of ultrasonic irradiation and temperature on fibrinolytic activity in vitro

Abd Al-Roof Higazi, Ioni Katz, Michael Mayer, Abraham Teddy Weiss

Journal:

Thrombosis Research

Year:

1993

Language:

english

File:

PDF, 228 KB

english, 1993

42

Tissue Factor Regulates Plasminogen Binding and Activation

Fan, Zhiqiang, Larson, Peter J., Bognacki, John, Raghunath, P.N., Tomaszewski, John E., Kuo, Alice, Canziani, Gabriela, Chaiken, Irwin, Cines, Douglas B., Higazi, Abd Al-Roof

Journal:

Year:

1998

File:

PDF, 264 KB

1998

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